Fernando MCV Reis

The paper identifies a genetically-defined population of cck-expressing cells in the lateral and ventrolateral PAG that selectively promote flight to safety, revealing a molecular axis of functional organization in the PAG.

This study identifies the dorsal premammillary nucleus as a central node in the escape network by showing its role in controlling escape vigor from both innate and conditioned threats in mice and suggesting a similar pathway in humans.

The paper identifies threat-approach and threat-avoidance ensembles in the dPAG of mice and shows they encode distinct behavioral states.