Folate receptor overexpression shortens C. elegans lifespan by impeding adaptation to microbial metabolism
Bideep Shrestha, Milla Tallila, Olli Matilainen
This paper shows that overexpression of FOLR-1 in C. elegans shortens lifespan, dependent on gut microbiota, revealing a non-canonical role of folate receptors in aging.
bioRxiv · Jun 26, 2023 · PreprintGenetics