Refining bias correction in genome-wide association analyses of case-control studies
Behrooz Darbani, Ole Birger Pedersen, Sisse Rye Ostrowski, Qihua Tan, Vibeke Charlotte Andersen
This paper provides guidance for reducing bias in case-control GWAS by addressing genetic relatedness, allelic interactions, and control genotype biases, introducing the AlleliC-GWAS tool.
bioRxiv · Sep 1, 2025 · PreprintBioinformatics