Qihua Tan

This paper provides guidance for reducing bias in case-control GWAS by addressing genetic relatedness, allelic interactions, and control genotype biases, introducing the AlleliC-GWAS tool.

The paper identifies an association between ribosomal DNA copy number and body mass in humans and rats, showing it relates to growth rate and BMI but not obesity.

The paper evaluates 54 polygenic risk scores in long-lived individuals and their offspring, finding lower genetic risk for Alzheimer's, CAD, and lupus, but not for dementia in long-lived individuals.

This study identifies 15 genetic loci associated with muscle weakness in older adults through a large meta-analysis, revealing new pathways linked to aging and health outcomes.

This study investigates the causes of variation in DNA methylation age across the lifespan, finding that environmental factors, particularly shared ones, are the main drivers.

This study examines genetic and environmental influences on DNA methylation changes in aging twins over 10 years, finding genetic contributions to stability and environmental factors to novel methylation differences.

The paper identifies age-related DNA methylation patterns on the X-chromosome in males and females and finds sex differences in their association with mortality.