ND-13, a DJ-1 derived peptide, as a novel pharmacological approach in the prevention of NLRP3 inflammasome activity in Diabetic Nephropathy
María José Caballero-Herrero, Celia Arias-Sánchez, Ignacio Quevedo-Romero, Patricia S. Latham, Carmen De Miguel, Yihan Zhong, Gang-Gang Xu, Estela Guillén, Adrián Núñez-Sancho, Diego Angosto-Bazarra, Cristina Molina‐López, Laura Hurtado‐Navarro, Julieta Schachter, Luis Pardo-Marín, J. M. Castro Cerón, , Santiago Cuevas
This study investigates ND-13, a DJ-1-derived peptide, showing its ability to reduce NLRP3 inflammasome activity and renal damage in diabetic nephropathy models.
bioRxiv · Jan 21, 2025 · PreprintCell Biology