Transcriptomic signatures and network-based methods uncover new Senescent Cell Anti-Apoptotic Pathways and Senolytics
Samael Olascoaga, Mina Königsberg, Jesús Espinal Enríquez, Hugo Tovar, Félix Matadamas‐Martínez, Jaime Pérez‐Villanueva, Norma Edith López‐Díazguerrero
The paper identifies new senescent cell anti-apoptotic pathways and senolytics using transcriptomic data and network-based methods, validating Fluorouracil's senolytic activity through multiple targets.
FEBS Journal · Jan 27, 2025Peer-reviewedCell Biology