Samael Olascoaga

The paper identifies new senescent cell anti-apoptotic pathways and senolytics using transcriptomic data and network-based methods, validating Fluorouracil's senolytic activity through multiple targets.

This study examines SCAPs gene expression and co-expression patterns across tissues in young and elderly individuals, revealing tissue-specific variations and complex network rewiring rather than consistent age-related increases.

The paper identifies new senolytic drugs through computational methods, showing they target senescent cells by inhibiting multiple anti-apoptotic pathways.