Author

Alexis M. Nzila

King Fahd University of Petroleum and MineralsORCID 0000-0002-0148-7063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Beatrice Njeri IrunguiD· 1 shared Damaris Matoke-MuhiaiD· 1 shared Daniel Muthui KiboiiD· 1 shared Fagdéba David BaraiD· 1 shared Francis Thuo KimaniiD· 1 shared Gabriel N. MagomaiD· 1 shared Loise Ndung’uiD· 1 shared Noah Machuki OnchiekuiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Beatrice Njeri IrunguORCID

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1 paper

Recent·Most cited

Genetic alteration of ferredoxin NADP+-reductase or cysteine desulfurase in piperaquine-resistant Plasmodium berghei restores susceptibility to lumefantrine and abolishes the impact of probenecid, verapamil, and cyproheptadine

Fagdéba David Bara, Loise Ndung’u, Noah Machuki Onchieku, Beatrice Njeri Irungu, Simplice Damintoti Karou, Francis Thuo Kimani, Damaris Matoke-Muhia, Peter Mwitari, Gabriel N. Magoma, Alexis M. Nzila, Daniel Muthui Kiboi

The paper investigates how genetic alterations in SufS or FNR genes affect LM and PQ resistance in P. berghei and shows that these changes restore LM susceptibility and negate chemosensitizer effects.

bioRxiv · Sep 14, 2020 · PreprintGenetics