Author

Clíona Farrell

UK Dementia Research InstituteORCID 0000-0002-0148-9771Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Christina E. ToomeyiD· 1 shared Elizabeth HeadiD· 1 shared Elizabeth J. AndrewsiD· 1 shared Eric W. Doran· 1 shared Frances K. WisemaniD· 1 shared Jenny HällqvistiD· 1 shared Kevin A. MillsiD· 1 shared Lisi Flores AguilariD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Christina E. ToomeyORCID

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1 paper

Recent·Most cited

Apolipoprotein E abundance is elevated in the brains of individuals with Down syndrome-Alzheimer's disease

Clíona Farrell, Yazead Buhidma, Paige Mumford, Wendy Heywood, Jenny Hällqvist, Lisi Flores Aguilar, Elizabeth J. Andrews, Negin Rahimzadah, Orjona Stella Taso, Eric W. Doran, Vivek Swarup, Elizabeth Head, Tammaryn Lashley, Kevin A. Mills, Christina E. Toomey, Frances K. Wiseman

The paper compares proteome and transcriptome changes in DSAD brains to AD and healthy controls, finding elevated APOE in specific cell types.

Acta Neuropathologica · May 19, 2025Peer-reviewedNeuroscience