Variation in virion phosphatidylserine content drives differential GAS6 binding among closely related flaviviruses
Lizhou Zhang, Byoung-Shik Shim, Claire E. Kitzmiller, Young‐Chan Kwon, Audrey Stéphanie Richard, Michael Farzan, Hyeryun Choe
The paper identifies variation in virion phosphatidylserine content as the reason for differential GAS6 binding among flaviviruses, explaining ZIKV's unique ability to use AXL for entry.
Journal of Virology · Sep 24, 2025Peer-reviewedMicrobiology