Author

John E. Adams

Vanderbilt UniversityORCID 0000-0002-0213-530XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:software / tool· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

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Benjamin K. Kesler· 1 shared Blythe G Hospelhorn· 1 shared Gregor NeuertiD· 1 shared Jason J HughesiD· 1 shared

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2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperSystems Biology

Benjamin K. Kesler

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1 paper

Recent·Most cited

Systems BiologybioRxivPreprintAug 14, 2025

TrueProbes: Quantitative Single-Molecule RNA-FISH Probe Design Improves RNA Detection

Jason J Hughes, Benjamin K. Kesler, John E. Adams…·Gregor Neuert

TrueProbes improves RNA detection by designing high-specificity smRNA-FISH probes using BLAST analysis and thermodynamic modeling, outperforming existing tools in computational and experimental metrics.

DOI 10.1101/2025.08.14.670355

spatial transcriptomicsstatistical model

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