Elisa Posani

This paper evaluates blind predictions of dynamic water and ion ensembles around RNA using cryo-EM densities from CASP16, finding that molecular dynamics approaches perform best.

The paper refines cryo-EM RNA structures using all-atom simulations and metainference to account for structural flexibility, revealing inaccuracies in single-structure approaches.

This study analyzes the temporal evolution of SARS-CoV-2 codon usage across 134,905 genomes, finding divergence in genes N and S with more optimized codon usage for human hosts.