Xinyi Li

SheepEpimap combines 516 histone CUT&Tag, ATAC-seq and RNA-seq datasets from 43 sheep tissues to annotate 2.93 million cis-regulatory elements and 145,407 allele-specific variants for trait interpretation.

The paper determines the optimal dose of concanavalin for a liver failure mouse model and investigates the role of IL-35 and glucocorticoids in immunoregulation and disease progression.

This paper introduces cov-LDSC, a method to estimate heritability and its enrichment in tissue-specific gene sets in admixed populations, showing high concordance across populations but population-specific differences for some traits.