Zhangyuan Pan

SheepEpimap combines 516 histone CUT&Tag, ATAC-seq and RNA-seq datasets from 43 sheep tissues to annotate 2.93 million cis-regulatory elements and 145,407 allele-specific variants for trait interpretation.

The paper presents a multi-tissue sheep atlas identifying regulatory variants and their effects on molecular phenotypes, revealing allelic heterogeneity and evolutionary patterns.

The paper constructs a bovine epigenomic atlas to annotate regulatory elements and decode the regulatory syntax of the cattle genome, aiding in fine-mapping GWAS loci for complex traits.

The ChickenGTEx project provides a multi-tissue reference of regulatory variants in chicken, analyzing their functional impacts and utility in genetics, genomics, and evolutionary studies.

This study analyzes the CASP14 gene's tissue-specific expression and functional loci in sheep horns using RNA-Seq, WGS, and KASP assays, identifying three potential functional sites linked to horn development.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

This study identifies selection signatures and loci associated with complex traits in pigs by analyzing multi-omics data from Eastern and Western breeds.

This paper develops DeepGCF, a deep learning method to predict functional conservation between human and pig using epigenome and transcriptome data, showing improved performance and insights into regulatory and heritability patterns.

The paper builds a TE atlas in pigs, showing young SINEs' roles in gene regulation, genetic diversity, and complex traits through multi-omics analysis.