Xiao Chang

This study identifies a novel genetic locus near SOX5 and reveals causal links between psychiatric and metabolic factors in anorexia nervosa using integrative GWAS and cross-trait analysis.

This paper identifies and validates 5q31.1 as a neuroblastoma susceptibility locus in Chinese children through GWAS and functional studies.

This paper conducts a multi-ancestry GWAS meta-analysis of suicide attempt, identifying 12 genome-wide significant loci and finding shared genetic risks with ADHD, smoking, and risk tolerance.

This study identifies 22 novel genetic loci associated with low polygenic risk score type 1 diabetes by analyzing rare variants in two independent cohorts.

This study identifies genetic correlations between COVID-19 and various diseases and traits using GWAS data, validating known risk factors and reporting novel associations.

This paper develops a machine learning model to interpret DNA variants in MODY genes using ACMG criteria, achieving over 95% accuracy for gene-specific classification.