Building The Human Genotype-Phenotype Map to Harness Pleiotropy and Refine Disease Mechanisms
Andrew R. Elmore, Aimee Hanson, Genevieve M Leyden, James Johnson, George Davey Smith, Lavinia Paternoster, Tom R. Gaunt, Gibran Hemani
The paper introduces GPMap, a resource that maps genetic associations across traits and molecular measurements to identify pleiotropy and improve disease mechanism understanding.
medRxiv · Feb 20, 2026 · PreprintGenetic & Genomic Medicine