Hypoxia drives asymmetric envelope remodelling to promote membrane adaptation and antibiotic tolerance in mycobacteria
Lydia Mathew, Tzong-Hsien Lee, Marie‐Isabel Aguilar, Shobhna Kapoor
This study shows hypoxia causes asymmetric remodeling of mycobacterial envelopes, leading to antibiotic tolerance by altering membrane order and hydration.
bioRxiv · Sep 18, 2026 · PreprintBiophysics