Author

Lydia Mathew

Indian Institute of Technology BombayORCID 0000-0001-5794-8554Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:metagenomics· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Shobhna KapooriD· 3 shared Akira Okano· 1 shared Assirbad Behura· 1 shared Aswin T. SrivatsaviD· 1 shared Atsuko IkedaiD· 1 shared Ayaka Hirota· 1 shared Ayush Panda· 1 shared Debraj KoiriiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

Shobhna KapoorORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintSep 18, 2026

Hypoxia drives asymmetric envelope remodelling to promote membrane adaptation and antibiotic tolerance in mycobacteria

Lydia Mathew, Tzong-Hsien Lee, Marie‐Isabel Aguilar, Shobhna Kapoor

This study shows hypoxia causes asymmetric remodeling of mycobacterial envelopes, leading to antibiotic tolerance by altering membrane order and hydration.

DOI 10.64898/2026.09.12.751103

experimental assay

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Cell BiologybioRxivPreprintAug 5, 2026

Pathogenic Bacteria Remotely Remodel Host Membrane Mechanics via Extracellular Vesicles to subvert Phagosome Maturation and Promote infection

Debraj Koiri, Lydia Mathew, Ayush Panda…·Mohammed Saleem

This study shows pathogenic bacteria use extracellular vesicles to alter host membrane mechanics, preventing phagosome maturation and aiding infection.

DOI 10.64898/2025.12.17.694930

humanproteomics

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Cell BiologybioRxivPreprintJun 6, 2026

Sphingolipids integrate TORC2 with TORC1 through vacuolar liquid-ordered domain formation

Hiroto Denda, Katsuki Eto, Kazue Nishiyama…·Kouichi Funato

The paper shows sphingolipids link TORC2 and TORC1 via vacuolar liquid-ordered domains, integrating signaling pathways across cellular compartments.

DOI 10.64898/2026.06.03.729730

yeastexperimental assay

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