Author

Ryan Mehlem

Clemson UniversityORCID 0000-0002-0243-262XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:fungi (other)· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Nava Raj PoudyaliD· 2 shared Sourabh DhingraiD· 2 shared Garrett Kaufman· 1 shared Jason StajichiD· 1 shared Maximiliano OrtiziD· 1 shared Priyanka Doneparthi· 1 shared Ritu Devkota· 1 shared Rooksana E. NooraiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

Nava Raj PoudyalORCID

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2 papers

Recent·Most cited

A long non-coding RNA regulates in vitro and in vivo triazole antifungal susceptibility in Aspergillus fumigatus

Nava Raj Poudyal, Ryan Mehlem, Priyanka Doneparthi, Tabitha Cady, Garrett Kaufman, Sven D. Willger, Maximiliano Ortiz, Rooksana E. Noorai, Jason Stajich, Sourabh Dhingra

The paper identifies a long non-coding RNA, afu-182, that regulates azole antifungal susceptibility in Aspergillus fumigatus both in vitro and in vivo.

Genetics · Jun 15, 2026Peer-reviewedMolecular Biology

Thermal adaptation crosstalk with azole response through lncRNA in Aspergillus fumigatus

Nava Raj Poudyal, Ryan Mehlem, Ritu Devkota, Sourabh Dhingra

The paper shows that thermal adaptation in Aspergillus fumigatus affects azole drug response via lncRNA afu-182, with lower RNA levels at higher temperatures linked to worse disease outcomes.

bioRxiv · May 19, 2026 · PreprintMicrobiology