NeuroscienceJournal of NeuroinflammationPeer-reviewed
Fibrotic lung-derived sphingosine-1-phosphate drives emotion-like disorders by regulating hippocampal neuroinflammation and cell death
Zhihao Xu, Xu Deshang, Keqin Liu…·Juntang Lin
This study shows that S1P from fibrotic lungs causes neuroinflammation and mood disorders by acting on the hippocampus, and inhibiting S1P pathways can alleviate these effects.
DOI 10.1186/s12974-026-03984-z