GenomicsbioRxivPreprint
Widespread 3' UTR splicing regulates expression of oncogene transcripts in sequence-dependent and independent manners
Jack J. Riley, Cristina N. Alexandru-Crivac, Sam Bryce-Smith…·Ian M. Sudbery
The paper identifies widespread 3' UTR splicing in cancer, showing it regulates oncogene expression through NMD-dependent and -independent mechanisms, with specific examples in colon cancer.
DOI 10.1101/2024.01.10.575007