Mechanistic dissection of global proteomic changes in rats with heart failure and preserved ejection fraction
Daniel Soetkamp, Aleksandra Binek, Romain Gallet, Geoffrey de Couto, Peter J. Kilfoil, Rowann Mostafa, Vidya Venkatraman, Ronald J. Holewinski, Amy D. Bradshaw, Joshua I. Goldhaber, Michael R. Zile, Eduardo Marbán, Jennifer E. Van Eyk
This paper identifies key transcription and translation regulators affected by CDC treatment in rat HFpEF, correlating their levels with diastolic function improvements.
bioRxiv · Sep 6, 2021 · PreprintMolecular Biology