Vidya Venkatraman

Mechanistic dissection of global proteomic changes in rats with heart failure and preserved ejection fraction

This paper identifies key transcription and translation regulators affected by CDC treatment in rat HFpEF, correlating their levels with diastolic function improvements.

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

The paper performs an integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients to identify dysregulated pathways and validate them in vivo and in postmortem data.

Quantitative Method for Assessing the Role of Lysine & Arginine Post-Translational Modifications in Nonalcoholic Steatohepatitis

The paper introduces a method to quantify lysine and arginine PTMs in NASH using mass spectrometry and applies it to mouse liver lysates, finding altered methylation and acetylation in NASH.

Identifying high-priority proteins across the human diseasome using semantic similarity

The paper identifies high-priority proteins across the human diseasome using semantic similarity and provides a systematic collection of popular proteins across diseases, phenotypes, and pathways.

Proteomic Architecture of Human Coronary and Aortic Atherosclerosis

The paper analyzes the proteomic architecture of human coronary and aortic atherosclerosis using mass spectrometry data from 200 specimens, identifying key protein networks and regulatory features associated with early disease.