Bruno Jorge de Andrade Silva

Side-by-side PBMC and CD8+ TEMRA profiling shows Parse favors longer transcripts but underdetects cytotoxic genes (GNLY, PRF1, GZMB), so 10X Chromium better resolves TEMRA subsets.

This study identifies CD1a-restricted T cell responses to canonical microbial peptides in leprosy, expanding the known ligands of CD1a and suggesting potential applications for mycobacterial immunity research.

This study identifies TREM2+ lipid-laden macrophages in alveolar TB pneumonia that support Mtb survival, contrasting with granulomas, and shows pharmacological reversal of this immunometabolic state.