Author

Lilia Weizel

Goethe University FrankfurtORCID 0000-0002-0373-2114Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Aimo KanntiD· 2 shared Ewgenij ProschakiD· 2 shared Julia Schönfeld· 2 shared Kerstin HiesingeriD· 2 shared Nick Liebisch· 2 shared Stefan KnappiD· 2 shared Steffen Brunst· 2 shared Adarsh M. KumariD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Aimo KanntORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Medicinal ChemistryPeer-reviewedJun 18, 2025

STRUCTURE-BASED DESIGN OF PROTACS FOR THE DEGRADATION OF SOLUBLE EPOXIDE HYDROLASE

Julia Schönfeld, Steffen Brunst, Ludmila Ciomirtan…·Kerstin Hiesinger

This paper designs and tests sEH-PROTACs to degrade soluble epoxide hydrolase, identifying PROTAC 23 as effective in degrading sEH in human macrophages.

11 citations

humanprotein structure

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Cell BiologyChemical CommunicationsPeer-reviewedJan 1, 2025

Click Chemistry Enables Rapid Development of Potent sEH PROTACs Using a Direct-to-Biology Approach

Julia Schönfeld, Nick Liebisch, Steffen Brunst…·Kerstin Hiesinger

This paper develops a miniaturized Direct-to-Biology platform for rapid PROTAC degrader synthesis and screening, identifying potent sEH degraders with subnanomolar activity.

12 citations

experimental assaydrug response / drug discovery

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