Author

Andy Brass

University of ManchesterORCID 0000-0002-0389-7058Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

EM Navarro-López· 1 shared JL Hernández-DomíngueziD· 1 shared May TassabehjiiD· 1 shared Nikita AbramovsiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 2 mutual co-author links

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1 shared paperBioinformatics

EM Navarro-López

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2 papers

Recent·Most cited

BioinformaticsFrontiers in GeneticsPeer-reviewedMar 13, 2020

Hardy-Weinberg Equilibrium in the Large Scale Genomic Sequencing Era

Nikita Abramovs, Andy Brass, May Tassabehji

The paper identifies heterozygote excess variants in genomic data from 137,842 individuals, finding many enriched in recessive disease genes and suggesting potential heterozygote advantages.

116 citationstop 3%

humanwhole-genome sequencing

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BioinformaticsbioRxivPreprintJun 12, 2019

The transcription factor basal regulatory network of Homo sapiens and Saccharomyces cerevisiae: uncovering the relationship between topology and phenotype

JL Hernández-Domínguez, Andy Brass, EM Navarro-López

The paper examines the relationship between topological features of the transcription factor basal regulatory network and phenotypes in humans and yeast, finding correlations with cancer and genetic diseases.

DOI 10.1101/669697

humanyeast

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