Increased FAN1 expression by mRNA-LNP attenuates CAG repeat expansion in Huntington patients' iPSC-derived astrocytes
Yung‐Chih Cheng, Gosia Nocula-Lugowska, Julita A Ramirez…·Shian-Huey Chiang
The paper shows that increasing FAN1 expression in HD patient astrocytes reduces CAG repeat expansion using mRNA-LNP.