Author

Takashi Kimura

Hyogo Medical UniversityORCID 0000-0002-0401-7227Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Harutoshi Fujimura· 3 shared Kenji Jinnai· 3 shared Masamitsu Nishi· 2 shared Masataka IgetaiD· 2 shared Tsuyoshi MatsumuraiD· 2 shared Brittney A. OteroiD· 1 shared Charles A. ThorntoniD· 1 shared Eric T. WangiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Harutoshi Fujimura

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3 papers

Recent·Most cited

Analysis of splicing abnormalities in the white matter of myotonic dystrophy type 1 brain using RNA-sequence

Kazuki Yoshizumi, Masamitsu Nishi, Masataka Igeta, Masayuki Nakamori, Tsuyoshi Matsumura, Harutoshi Fujimura, Kenji Jinnai, Takashi Kimura

This study investigates splicing abnormalities in white matter of DM1 brains using RNA-seq, finding that WM defects may result from both GM and WM RNA splicing issues.

bioRxiv · Dec 23, 2022 · PreprintMolecular Biology

Transcriptome Alterations in Myotonic Dystrophy Frontal Cortex

Brittney A. Otero, Kiril Poukalov, Ryan P. Hildebrandt, Charles A. Thornton, Kenji Jinnai, Harutoshi Fujimura, Takashi Kimura, Katharine A. Hagerman, Jacinda B. Sampson, John Day, Eric T. Wang

The paper analyzes RNA-seq transcriptomes from frontal cortex tissue of DM1 and DM2 patients to identify splicing changes and their implications for CNS dysfunction.

Cell Reports · Jan 1, 2021Peer-reviewedGenetics

Differences in splicing defects between the grey and white matter in myotonic dystrophy type 1

Masamitsu Nishi, Takashi Kimura, Masataka Igeta, Mitsuru Furuta, Koichi Suenaga, Tsuyoshi Matsumura, Harutoshi Fujimura, Kenji Jinnai, Hiroo Yoshikawa

The paper examines splicing defects in grey and white matter of DM1 patients, finding greater PSI changes in grey matter compared to white matter.

PLoS ONE · May 14, 2020Peer-reviewedMolecular Biology