Biomimetic fractal topography enhances podocyte maturation in vitro
Chuan Liu, Praful Aggarwal, Karl T. Wagner, Shira Landau, Teng Cui, Xin Song, Laleh Shamaei, Naimeh Rafatian, Yimu Zhao, Sonia Rodríguez‐Ramírez, Keith J. Morton, Elizabeth Virlee, Chen Yu Li, Dawn Bannerman, Simon Pascual‐Gil, , Milica Radisic
This study shows that biomimetic fractal topography improves podocyte maturation in vitro by enhancing marker expression, cell polarity, and ECM remodeling via YAP signaling.
Nature Communications · Dec 15, 2025Peer-reviewedBioengineering