Naimeh Rafatian

This study uses single-cell RNA-seq to analyze transcriptional changes in mouse hearts during perinatal development, identifying gene regulatory patterns and a cell type-independent imprinted gene signature.

This paper introduces a heart-on-a-chip platform with ultrasoft mechanosensors to measure cell- and tissue-scale contractile stresses, showing that ECM composition affects contractility and drug responses.

This paper develops a patient-specific heart-on-a-chip model for dilated cardiomyopathy, showing functional abnormalities and drug response.

This study shows that biomimetic fractal topography improves podocyte maturation in vitro by enhancing marker expression, cell polarity, and ECM remodeling via YAP signaling.

This study shows that a myosin ATPase inhibitor reverses HCM phenotypes in pediatric iPSC-cardiomyocytes, with effects dependent on the underlying genetic variant.