Author

Tobias Plowman

The Francis Crick InstituteORCID 0000-0002-0413-0975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

George KassiotisiD· 2 shared Callum HalliD· 1 shared Jane Ho Chun LoongiD· 1 shared Judith PapeiD· 1 shared Laura E. Doglio· 1 shared R. Houston ThompsoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersGenomics

George KassiotisORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintOct 23, 2026

Nonsense-mediated decay constrains transposable element-driven evolutionary innovation

Tobias Plowman, George Kassiotis

This study shows NMD limits TE-driven transcriptomic innovation by degrading TE-derived transcripts, affecting evolutionary novelty and cancer outcomes.

DOI 10.64898/2026.10.22.760879

humanlong-read sequencing

𝕏 PostBluesky

GenomicsGenome MedicinePeer-reviewedMay 7, 2025

Retroelement co-option disrupts the cancer transcriptional programme

Jane Ho Chun Loong, R. Houston Thompson, Callum Hall…·George Kassiotis

This study shows that cancer-specific activation of retroelements disrupts gene function and tumour-promoting genes, with clinical and experimental evidence supporting these effects.

8 citations

humanbulk RNA-seq

𝕏 PostBluesky