Shiqiang Zhang

This study shows PPARγ suppresses cytosolic DNA-induced macrophage inflammation by reprogramming metabolism and inhibiting inflammatory gene expression through super-enhancer remodeling.

The paper identifies alveolar macrophage-specific oncostatin M as a driver of pulmonary fibrosis in PCV2d infection and shows targeting it reduces fibroblast activation.

The paper identifies a positive feedback loop regulating ERK phosphorylation in mESCs through the Etv5-Tet2-Fgfr2 axis, showing Etv5 influences Fgfr2 expression via Tet2-mediated DNA methylation.