Yan Wang

This study shows that elamipretide improves oocyte quality and fertility in aged females by enhancing nuclear and cytoplasmic maturation through the VEGF signaling pathway.

The paper identifies alveolar macrophage-specific oncostatin M as a driver of pulmonary fibrosis in PCV2d infection and shows targeting it reduces fibroblast activation.

This study identifies two conserved effector families from fungal pathogens that trigger cell death in plants, showing they are recognized by immune receptors.

TSD is a tool for discovering complex structural variants using PacBio targeted sequencing data, showing better performance than other tools in detecting complex genomic structural variants.

The paper identifies a positive feedback loop regulating ERK phosphorylation in mESCs through the Etv5-Tet2-Fgfr2 axis, showing Etv5 influences Fgfr2 expression via Tet2-mediated DNA methylation.

MECAT provides an ultra-fast tool for mapping, error correction, and de novo assembly of single-molecule sequencing reads, achieving high-quality assemblies with reduced computational cost.