Germline gene de-silencing by a transposon insertion is triggered by an altered landscape of local piRNA biogenesis
Danny E. Miller, Kelley Van Vaerenberghe, Angela Li, Emily K. Grantham, Celeste Cummings, Marilyn Barragan, Rhonda Egidy, Allison R. Scott, Kate Hall, Anoja G. Perera, William D Gilliland, Justin P. Blumenstiel
The paper shows how a transposon insertion can trigger germline gene silencing via piRNA biogenesis and how a second insertion can reverse this silencing by altering the same process.
bioRxiv · Jun 26, 2020 · PreprintGenetics