Author

Keith R. Curtis

Fred Hutch Cancer CenterORCID 0000-0002-0453-7222Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Loı̈c Le MarchandiD· 2 shared Albert de la ChapelleiD· 1 shared Amanda Ewart TolandiD· 1 shared Amanda Jane CrossiD· 1 shared Amit D. JoshiiD· 1 shared Andrea GsuriD· 1 shared Andrea N. Burnett‐HartmaniD· 1 shared Andrew Tan ChaniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Loı̈c Le MarchandORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintApr 10, 2026

Gut Microbiota Mediates the Association between Diet Quality and Ectopic Adiposity: The Multiethnic Cohort Adiposity Phenotype Study

Songran Wang, Meredith A.J. Hullar, Keith R. Curtis…·Timothy W. Randolph

This study shows that higher diet quality reduces ectopic adiposity, and this effect is partially mediated by gut microbiota, specifically four bacterial genera.

DOI 10.64898/2026.04.10.717245

humanbulk RNA-seq

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Genetic & Genomic MedicineGutPeer-reviewedFeb 25, 2021

Genetic architectures of proximal and distal colorectal cancer are partly distinct

Jeroen R. Huyghe, Tabitha A. Harrison, Stephanie A. Bien…·Rachel Pearlman

This study identifies 13 new genetic loci specific to proximal or distal colorectal cancer subtypes, revealing partly distinct genetic architectures for these tumor locations.

80 citations

humanGWAS summary statistics

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