Rachel Pearlman

Global Proteomic Analysis of Colorectal Cancers Stratified by Microsatellite Instability Subtype Reveals Protein Differences

This study performs a global proteomic analysis of colorectal cancers stratified by microsatellite instability subtype, revealing protein differences associated with Lynch syndrome and other subtypes.

Large-scale alternative polyadenylation (APA)-wide association studies to identify putative susceptibility genes in human common cancers

The paper identifies 58 risk genes associated with common cancers by linking genetically predicted APA levels to cancer risk using GWAS data.

Combining Asian-European Genome-Wide Association Studies of Colorectal Cancer Improves Risk Prediction Across Race and Ethnicity

This study improves polygenic risk scores for colorectal cancer by combining Asian and European ancestry data, enhancing risk prediction across diverse racial and ethnic groups.

Genetic architectures of proximal and distal colorectal cancer are partly distinct

This study identifies 13 new genetic loci specific to proximal or distal colorectal cancer subtypes, revealing partly distinct genetic architectures for these tumor locations.