Author

Yirui Hu

Geisinger Health SystemORCID 0000-0002-0477-0155Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electronic health records· 2 Research Focus:GWAS / association mapping· 2 Organism:human· 2 Approach:statistical model· 2 Approach:machine learning (classical)· 1

Frequent Co-Authors

Christopher F. ChabrisiD· 2 shared Colin G. WalshiD· 2 shared Daniel RochaiD· 2 shared Drew WilimitisiD· 2 shared Michael A. RippergeriD· 2 shared Richard Karlsson LinnériD· 2 shared David BursteiniD· 1 shared Douglas M. RuderferiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Christopher F. ChabrisORCID

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2 papers

Recent·Most cited

Genome-wide association study of treatment resistant depression highlights shared biology with metabolic traits

Jooeun Kang, Victor Manuel Castro, Michael A. Ripperger, Sanan Venkatesh, David Burstein, Richard Karlsson Linnér, Daniel Rocha, Yirui Hu, Drew Wilimitis, Theodore J. Morley, Lide Han, Rachel Youngjung Kim, Yen‐Chen Anne Feng, Tian Ge, Stephan Heckers, , Douglas M. Ruderfer

This study uses EHR data to estimate TRD probability and identifies two genome-wide significant loci linked to metabolic traits, suggesting shared biology with related conditions.

American Journal of Psychiatry · May 15, 2024Peer-reviewedGenetic & Genomic Medicine

Association Between Psychiatric Polygenic Scores, Healthcare Utilization and Chronic Disease Comorbidity Burden Among European Ancestry Individuals

Henry Lester Kirchner, Daniel Rocha, Richard Karlsson Linnér, Drew Wilimitis, Colin G. Walsh, Michael A. Ripperger, Hyunjoon Lee, Zhaowen Liu, Lea Karatheodoris Davis, Yirui Hu, Christopher F. Chabris, Jordan W. Smoller

The paper examines the association between psychiatric polygenic scores and healthcare utilization and comorbidity burden in individuals of European ancestry, finding significant links for major depressive disorder.

medRxiv · Sep 29, 2023 · PreprintGenetic & Genomic Medicine