A Machine Learning and Bioinformatic Analysis Reveals an Associated between Cell Surface Receptor Transcript Levels with Drug Response of Breast Cancer Cells and the Drug Off-Target Effects
Musalula Sinkala, Krupa Naran, Dharanidharan Ramamurthy, Neelakshi Mungra, Darren Patrick Martin, Stefan Barth
The paper links drug response in breast cancer cells to cell surface receptor (CSR) transcript levels and reveals off-target effects through analysis of transcriptional landscapes and clinical data.
bioRxiv · Aug 31, 2022 · PreprintBioinformatics