Laurent Le

BrightEyes-Scope: A Reference Implementation for Image Scanning Microscopy with SPAD Array Detection

BrightEyes-Scope provides a reference implementation for SPAD array-based image scanning microscopy, offering guidelines for system construction and image reconstruction to improve super-resolution imaging.

Independent noise realizations enable morphologically agnostic image reconstruction in single-photon-sensitive microscopy

This paper introduces a morphology-agnostic regularization framework for image deconvolution in single-photon-sensitive microscopy, eliminating semi-convergence and improving reconstruction quality.

Brightness demixing for simultaneous multi-target imaging in 3D single-molecule localization microscopy

This paper introduces Brightness Demixing, a method for distinguishing multiple fluorophores in SMLM by using brightness instead of spectral separation, enabling multi-target imaging in 2D and 3D.