MECP2 duplication and mutations impair NSCs differentiation via miR-197 regulated ADAM10
Yumeng Wang, Yufang Zheng, Si-Yu Yang, Yang Zhang-min, Linna Zhang, Yan-Qin He, Xiaohong Gong, Dong Liu, Richard H. Finnell, Zilong Qiu, Yasong Du, Hongyan Wang
This study shows that MECP2 duplication and mutations impair neural stem cell differentiation through miR-197 regulation of ADAM10 and NOTCH signaling.
bioRxiv · May 2, 2018 · PreprintDevelopmental Biology