Hybrid Ornstein-Uhlenbeck-Branching Modeling of Pediatric Leukemia Evolution: A Computational Extension and Cohort-Level Application
This paper develops a computational model to simulate clonal evolution in pediatric leukemia using a hybrid OU-Branching framework and applies it to clinical data to study relapse patterns and therapeutic response.
bioRxiv · Nov 7, 2025 · PreprintCancer Biology