Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts
Hemant Suryawanshi, Hua Yang, Michelle Lubetzky, Pavel S Morozov, Mila Lagman, Gaurav Thareja, Alicia Alonso, Carol Y. Li, Catherine Snopkowski, Aziz Belkadi, Franco B. Mueller, John R. Lee, Darshana M. Dadhania, Steven Salvatore, Surya V. Seshan, , Thangamani Muthukumar
This study uses scRNA-seq to analyze kidney allograft biopsies and identifies recipient-derived fibroblasts and other cell states associated with fibrosis and rejection.
PLoS ONE · Jun 3, 2022Peer-reviewedMolecular Biology