Thangamani Muthukumar

The paper quantifies the direct relationship between Banff acute lesion scores and a urinary cell three-gene signature, showing strong associations with acute rejection pathology.

This study uses single-cell RNA sequencing to show that SOCE blockers BTP2 and CM4620 reduce cytotoxicity in CD8 T cells and NK cells while preserving anti-inflammatory programs in CD4 Tregs.

The paper identifies galectin-3 as a target for nanotherapeutic delivery of ruxolitinib to reduce GVHD-related kidney injury and systemic inflammation.

This study uses scRNA-seq to analyze kidney allograft biopsies and identifies recipient-derived fibroblasts and other cell states associated with fibrosis and rejection.

The paper examines cell-type-specific expression of RAS components across 141 cell types using scRNA-seq and links ACE2 expression to SARS-CoV-2 infection mechanisms.

The paper predicts long-term kidney graft function using exome sequencing by analyzing amino acid mismatches between recipients and donors.