Cancer BiologyCancer Immunology ResearchPeer-reviewed
Inhibition of PIM kinase in tumor associated macrophages suppresses inflammasome 1 activation and sensitizes prostate cancer to immunotherapy
Amber N. Clements, Andrea L. Casillas, Caitlyn E. Flores…·Noel A. Warfel
This study shows that inhibiting PIM kinases in tumor-associated macrophages reduces inflammasome activation and improves response to immunotherapy in prostate cancer.
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