César Payán‐Gómez

RNA sequence analysis of somatic mutations in aging and Parkinson's Disease

The paper analyzes RNA-seq data from Parkinson's Disease patients and controls to find increased somatic mutations in PD, with some clonal mutations being protective.

Orthogonal analysis of mitochondrial function in Parkinson's disease patients

This study investigates mitochondrial function in blood cells and dopamine neurons from Parkinson's disease patients, showing mitochondrial abnormalities and reversible alterations in some cell types.

Reduced frequency of clonal hematopoiesis in Parkinson's disease

The paper examines the association between clonal hematopoiesis and Parkinson's disease using whole exome sequencing data from controls and patients.

Peripheral mitochondrial function correlates with clinical severity in idiopathic Parkinson’s disease

The paper correlates peripheral mitochondrial function with clinical severity in idiopathic Parkinson’s disease, finding stronger correlations with non-dopaminergic signs and reversible mitochondrial defects under metabolic stress.