Dose Escalation in Pentylenetetrazol Kindling Detects Differences in Chronic Seizure Susceptibility
Mitchell Moyer, Jenna Langbein, Orest Tsymbalyuk, Darrian McAfee, Chixiang Chen, Muznabanu Bachani, Volodymyr Gerzanich, J. Marc Simard, Alexander Ksendzovsky
This paper introduces a novel PTZ Dose Escalation model to improve detection of chronic seizure susceptibility differences compared to standard PTZ kindling methods.
Epilepsy Research · Feb 13, 2026Peer-reviewedNeuroscience