Influenza A virus H5Nx genotypes assigned by genetic similarity are incongruent with global phylogenies
Angela McLaughlin, Hoc Tran, Deanna Tait, Huu-Tai Nguyen, Josip Rudar, Jolene A. Giacinti, Anthony V. Signore, Oliver Lung, Yohannes Berhane, Zvonimir Poljak, Finlay Maguire
This paper evaluates H5Nx influenza virus genotyping tools and finds they often group viruses with distinct evolutionary histories due to reassortment and reference bias.
bioRxiv · Oct 30, 2026 · PreprintBioinformatics