Statistical Coupling Analysis Predicts Correlated Motions in Dihydrofolate Reductase
Thomas L. Kalmer, Christine Mae F. Ancajas, Cameron I. Cohen, Jade M. McDaniel, Abiodun Samuel Oyedele, Hannah L. Thirman, Allison S. Walker
This study uses statistical coupling analysis and molecular dynamics to show that dynamically coupled residues in DHFR influence evolution and allosteric communication.
The Journal of Physical Chemistry B · Oct 10, 2024Peer-reviewedBiochemistry