Author

Edward M. Sellers

ORCID 0000-0002-0669-2373Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

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Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Michael B. McDonnelliD· 1 shared William J. TyleriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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1 shared paperPharmacology & Toxicology

Michael B. McDonnellORCID

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1 paper

Recent·Most cited

Estimating Cardiac 5-HT2B Safety Margins for Repeated Low-Dose Psilocybin Using an Exposure-Response Model

William J. Tyler, Edward M. Sellers, Michael B. McDonnell

This paper develops an exposure-response model to estimate cardiac safety margins for repeated low-dose psilocybin, finding a large safety margin due to psilocin's low-efficacy partial agonism and short half-life.

bioRxiv · Jul 23, 2026 · PreprintPharmacology & Toxicology