A mouse model of classical trigeminal neuralgia via intradural compression of the trigeminal nerve
Mostafa Abdulrahim, Yanxia Chen, Sumil K. Nair, Qian Xu, Yaowu Zhang, Oishika Das, Ryan Gensler, James Feghali, A. Karim Ahmed, Christopher M. Jackson, Judy Huang, Youssef G. Comair, Chetan Bettegowda, Xinzhong Dong, Risheng Xu
This paper develops a mouse model of classical trigeminal neuralgia by intradural nerve root compression, showing neuropathic pain behaviors and pharmacological responsiveness.
The Journal of Headache and Pain · Dec 23, 2025Peer-reviewedNeuroscience